Patrick, or Gay Uncle Patrick (GUP, for short), has always loved his niece, Maisie, and nephew, Grant. When tragedy strikes and Maisie and Grant lose their mother and Patrick's brother has a health crisis of his own, Patrick finds himself suddenly taking on the role of primary guardian. Despite having a set of "Guncle Rules" ready to go, Patrick has no idea what to expect, having spent years barely holding on after the loss of his great love, a somewhat-stalled acting career, and a lifestyle not-so-suited to a six- and a nine-year-old. Quickly realizing that parenting--even if temporary--isn't solved with treats and jokes, Patrick's eyes are opened to a new sense of responsibility, and the realization that, sometimes, even being larger than life means you're unfailingly human.